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US 2020/0085941 A1Published application
Antigenic thermostable polio vaccines & related methods
AssigneeUniversal Stabilization Technologies, Inc.
InventorVictor Bronshtein
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Abstract
The disclosure concerns vaccines; and more particularly, highly antigenic thermostable vaccines configured for mucosal or transdermal delivery without reconstitution. Also disclosed are methods for formulating the highly antigenic thermostable vaccines.
Claims19
An antigenic thermostable vaccine composition containing virus, comprising in parts by weight:
- 10-20 parts of one or more potassium salts, wherein said one or more potassium salts are selected from those exhibiting less than 50% water activity in saturated solution;
- 5-20 parts of one or more amino acids, and
- 10-40 parts of one or more carbohydrates;
- wherein a combination of the potassium salts, amino acids and carbohydrates forms an anhydrous glassy matrix, and
- wherein the virus is immobilized in the anhydrous glassy matrix.
2 more elements
Dependencies are inferred from the claim text.