Compositions and methods for treatment of uremic cardiomyopathy
AssigneeMarshall University Research Corporation
InventorsZijian XIE, Joseph I. SHAPIRO, Jiang LIU
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Abstract
Methods for treating uremic cardiomyopathy are provided and include the step of administering a polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject in need thereof. The polypeptide anatagonist can further include a cell penetrating polypeptide. Methods of treating anemia, including anemia-associated with chronic kidney disease, are also provided.
Claims21
A method for treating uremic cardiomyopathy, comprising administering a polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject in need thereof, the uremic cardiomyopathy characterized by profound anemia, and the polypeptide antagonist administered in an amount sufficient to attenuate the profound anemia.
(canceled)
A method for treating anemia, comprising administering a polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject in need thereof.
Dependencies are inferred from the claim text.