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US 2020/0080095 A1Published application
Method for producing 3'-fucosyllactose using corynebacterium glutamicum
AssigneeSeoul National University R&Db Foundation
InventorsJin-Ho SEO, Sang-Min JUNG, Do-Haeng LEE, Hyeong-Do JEON
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Abstract
Disclosed is a method for producing 3′-fucosyllactose using a wild Corynebacterium glutamicum strain. In addition, using the Corynebacterium glutamicum strain, which is a GRAS strain, 3′-fucosyllactose can be produced at a high concentration, high yield and high productivity.
Claims7
Recombinant Corynebacterium glutamicum which is transformed to express α-1,3-fucosyltransferase, is transformed to express GDP-D-mannose-4,6-dehydratase, is transformed to express GDP-L-fucose synthase, and is transformed to express lactose permease,
- wherein the recombinant Corynebacterium glutamicum has phosphomannomutase and GTP-mannose-1-phosphate guanylyltransferase.
Dependencies are inferred from the claim text.