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US 2020/0071704 A1Published application
Organic acid synthesis from c1 substrates
AssigneeAlliance for Sustainable Energy, LLC
InventorsCalvin A. HENARD, Michael T. GUARNIERI
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Abstract
Presented herein are biocatalysts and methods for converting C1-containing materials to organic acids such as muconic acid or adipic acid.
Claims20
An engineered cell, comprising an exogenously added gene encoding a 3-dehydroshikimate dehydratase (AroZ), a protocatechuic acid decarboxylase (AroY), a catechol 1,2-dioxygenase (CatA), a phspho-2-dehydro-3-deoxyheptonate aldolase (AroG), an anthranilate synthase (TrpE), a phosphoenolpyruvate synthase, or a transketolase;
- wherein the engineered cell is able to convert a C1 substrate to an organic acid.
Dependencies are inferred from the claim text.