Fluorescent silane layers for detecting explosives
AssigneeInstitut Dr. Foerster GmbH & Co. KG
InventorsKnut Rurack, Mustafa Biyikal
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Abstract
Detection reagent for an analyte comprising an NOx group, wherein the detection reagent comprises an arylamine, and a structural formula of the arylamine is selected from the structural formulae 1, 2 and 3: or of the formulae 4 or 5: where R1 and R7 are selected from CO2or PhCO2X with X=4-iodophenyl; 4-bromophenyl or 4-chlorophenyl; 4-vinylphenyl or 4-allylphenyl; or R1 and R7 are selected from CO2Y or PhCO2Y with Y=2-methyl-3-pentyn-2-yl or 3-tert-butyl-4,4-dimethyl-1-pentyn-3-yl, or R7 is selected from CO2Z, PhCO2Z, C(O)NZ2 or PhC(O)NZ2 with (Z=alkyl, perfluoroalkyl, vinyl, allyl, homoallyl, aryl); where R2, R3, R4, and/or R5 are independently selected from H, F, an alkyl and an aryl; and where R6 is selected from an alkyl and an aryl.
Claims33
Detection reagent for an analyte comprising an NOx group, wherein the detection reagent comprises an arylamine, and a structural formula of the arylamine is selected from the structural formulae 1, 2 and 3:
- or of the formulae 4 and 5:
- where
- R1 and R7 are selected from CO2X and PhCO2X with X=4-iodophenyl;
- 4-bromophenyl, 4-chlorophenyl, 4-vinylphenyl or 4-allylphenyl;
- or
- R1 and R7 are selected from CO2Y and PhCO2Y with Y=2-methyl-3-pentyn-2-yl or 3-tert-butyl-4,4-dimethyl-1-pentyn-3-yl;
- or
- R7 is selected from CO2Z, PhCO2Z,C(O)NZ2 and PhC(O)NZ2 with Z=alkyl, perfluoroalkyl, vinyl, allyl, homoallyl, aryl;
- where
- R2, R3, R4 and R5 are independently selected from:
- H, F, alkyl, aryl;
- and
- R6 is selected from alkyl or aryl.
Analyte-sensitive layer for an analyte comprising an NOx group, comprising:
- a silicatic substrate,
- a detection reagent arranged directly, without involvement of a polymer layer, on the silicatic substrate, wherein the detection reagent is selected from a substance of one of the formulae 1 to 5:
- where
- R1 and R7 are selected from CO2X or PhCO2 with X=4-iodophenyl;
- 4-bromophenyl, 4-chlorophenyl, 4-vinylphenyl
- or
- 4-allylphenyl;
- or
- R1 and R7 are selected from CO2Y or PhCO2Y with Y=2-methyl-3-pentyn-2-yl or 3-tert-butyl-4,4-dimethyl-1-pentyn-3-yl;
- or
- R7 is selected from CO2Z, PhCO2Z, C(O)NZ2 or PhC(O)NZ2 with Y=alkyl, perfluoroalkyl, vinyl, allyl, homoallyl, aryl;
- where
- R2, R3, R4 and R5 are independently selected from:
- H, F, alkyl, aryl;
- and
- R6 is selected from alkyl or aryl,
- wherein the detection reagent is covalently bonded to the silicatic substrate at least via a —C—Si—C— bond and a surface concentration of the detection reagent on the analyte-specific layer is selected from 50-350 μmol/cm2;
- or
- the detection reagent has been adsorbed on the silicatic substrate, where its surface concentration is between 100-750 μmol/cm2, and
- wherein a fluorescence intensity of the detection reagent in the presence of the analyte changes with respect to a fluorescence intensity of the detection reagent in the absence of the analyte as a function of a concentration of the analyte.
Dependencies are inferred from the claim text.