T cells expressing chemokine receptors for treating cancer
OwnerShaun Reuss McCollinventor
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Abstract
The present disclosure relates to methods and products for preventing and/or treating cancer, and in particular to methods, cells and products for preventing and/or treating cancer using adoptive immunotherapies. In certain embodiments, the present disclosure provides a method of treating a subject suffering from, or susceptible to, a cancer associated with chemokine expressing cells, the method comprising exposing the subject to T cells expressing a receptor to the chemokine and thereby treating the subject.
Claims18
-25. (canceled)
A method of treating a subject suffering from, or susceptible to, a cancer associated with chemokine expressing cells, the method comprising exposing the subject to T cells expressing a receptor to the chemokine and thereby treating the subject.
A method of producing therapeutic T cells for adoptive immunotherapy for treating a cancer, the method comprising engineering the cells to express a chemokine receptor.
A chimeric antigen T cell engineered to express a chemokine receptor.
Dependencies are inferred from the claim text.