High water content ophthalmic devices
AssigneeBausch & Lomb Incorporated
InventorsIvan M. Nuñez, Katie L. Poetz, Joseph W. Hoff, Judith Chapman Morgan
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Abstract
An ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) a major amount of one or more first non-silicone-containing hydrophilic monomers; (b) one or more hydrophobic monomers; and (c) a crosslinking agent mixture comprising (i) one or more di-, tri- or tetra(meth)acrylate-containing crosslinking agents and (ii) one or more di-, tri- or tetracarbamate-containing crosslinking agents, wherein the ophthalmic device has an equilibrium water content of at least about 65 weight percent.
Claims23
An ophthalmic device which is a polymerization product of a monomeric mixture comprising:
- (a) a major amount of one or more first non-silicone-containing hydrophilic monomers;
- (b) one or more hydrophobic monomers;
- and (c) a crosslinking agent mixture comprising (i) one or more di-, tri- or tetra(meth)acrylate-containing crosslinking agents and (ii) one or more di-, tri- or tetracarbamate-containing crosslinking agents, wherein the ophthalmic device has an equilibrium water content of at least about 65 weight percent.
A method of making an ophthalmic device comprising
- (a) providing a monomeric mixture comprising (i) a major amount of one or more first non-silicone-containing hydrophilic monomers;
- (ii) one or more hydrophobic monomers;
- and (iii) a crosslinking agent mixture comprising (1) one or more di-, tri- or tetra(meth)acrylate-containing crosslinking agents and (2) one or more di-, tri- or tetracarbamate-containing crosslinking agents;
- (b) subjecting the monomeric mixture to polymerizing conditions to provide a polymerized device, and
- (c) extracting the polymerized device, wherein the ophthalmic device has an equilibrium water content of at least about 65 weight percent.
Dependencies are inferred from the claim text.