Methods and devices for improved signal detection from biological samples
AssigneeTheranos IP Company, LLC
InventorToan Huynh
Life of this patent
Estimating the term…
Abstract
Methods and devices are provided to provide clean signals even in the presence of spectral interference. At least some of these methods can be applied for cases when interfering signals are to be accounted for. These cases include, but are not limited to, hemolysis detection, icterus detection, and assays. They can be implemented in with data collected with spectrophotometers, instruments that can collect absorbance values at the few wavelengths of interest, and, in the case of the method based on background subtraction, simple imaging setups with only two filters (such as but not limited to narrow-band and wide-band) per absorption peak of interest.
Claims8
(canceled)
A method for use with a biological sample, the method comprising:
- using peak curvature to reduce interference in quantification of hemolysis in the biological sample.
A method for use with a biological sample, the method comprising:
- using background subtraction in detection of hemolysis and icterus in the biological sample.
(canceled)
A method for use with a biological sample, the method comprising:
- acquiring background-subtracted signals using a narrow-band optical filter and a wide-band optical filter;
- using background-subtracted signals for quantification of hemolysis and icterus in the biological sample.
8-14. (canceled)
Dependencies are inferred from the claim text.