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US 2020/0048674 A1Published application
Biosynthesis of bioorthogonal amino acids
AssigneeThe Regents of the University of California
InventorsMichelle C. Y. Chang, Jorge A. Marchand Benmaman, Monica E. Neugebauer
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Abstract
Recombinant enzymes BesA, BesB, BesC, BesD and/or BesE are used generate non-canonical amino acids comprising a useful functional group, such as an alkynlyl, alkenyl or halogen.
Claims18
A method comprising contacting a recombinant enzyme selected from BesA, BesB, BesC, BesD and BesE with a corresponding predetermined substrate under conditions wherein the enzyme catalyzes formation of a predetermined reaction product comprising a functional group that is an alkylyl, alkenyl or halogen.
Dependencies are inferred from the claim text.