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AssigneeInvista North America S.A R. L.
InventorsGary SMITH, Alex Van Eck CONRADIE, Gregory S. KIRBY, Paul S. PEARLMAN
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The present disclosure describes biocatalytic processes for producing a product, comprising providing an aqueous stream (AS) comprising at least one fermentable substrate and a gaseous stream (GS) comprising at least one of CO2/H2, H2, methane, and/or CO to a fermentation zone, wherein the GS and AS stream, are optionally contacted and/or mixed; the fermentation zone comprising at least one organism capable of metabolizing an AS substrate and a GS substrate, wherein the fermentation operates at conditions to mixotrophically metabolize at least one gaseous substrate in the GS and at least one substrate in the AS, producing the product. The present disclosure also describes compositions comprising an AS, a GS, and an organism, wherein the organism or an equivalent or engineered equivalent thereof is a methanotroph or a hydrogen-metabolizing or CO-metabolizing chemolithotrophic organism, and wherein the organism is capable of mixotrophic metabolism of at least one gaseous substrate in the GS and at least one substrate in the AS. The present disclosure also describes a process wherein said fermentation operates at conditions to mixotrophically metabolize at least H2 in the gaseous stream and glycerol and lactic acid in the aqueous stream. The present disclosure also describes a system for producing a fermentation or bio-derived product.
A biocatalytic process comprising:
A biocatalytic process comprising:
The process of any one of the preceding claims, wherein the aqueous stream comprises at least one of a spent fermentation stream, stillage from a bio-ethanol production process, thin stillage stream from a bio-ethanol production process, whole stillage stream from a bio-ethanol production process, and an aqueous stream comprising one or more of glycerol, carbohydrate, oligomers of carbohydrates, protein, carboxylic acid, acetic acid, and lactic acid.
The process of any one of the preceding claims, further comprising:
The process of any one of the preceding claims, wherein in the fermentation zone the gaseous stream substrate has a CO2:H2 molar ratio ranging from 0 to 0.35 mol CO2/mol H2.
The process of any one of the preceding claims, wherein the conditions to mixotrophically metabolize at least one gaseous substrate in the gaseous stream and at least one substrate present in the aqueous stream are a pH ranging from 6 to 8, a temperature ranging from 30° C. to 40° C., and a pressure of above 1 atm absolute.
The process of any one of the preceding claims, wherein the at least one organism comprises at least one of (1) a genetic alteration, (2) a chemical alteration, and (3) a non-naturally occurring alteration.
A biocatalytic process comprising:
The process of any one of the preceding claims, wherein the fermentation or bio-derived product comprises a volatile product.
The process of any one of the preceding claims, wherein the fermentation or bio-derived product comprises at least one alkene precursor chosen from 3-hydroxy-enoic acid, an enol, and a 3-hydroxyacid or derivative thereof.
The process of any one of the preceding claims, wherein the fermentation or bio-derived product comprises one or more compounds, or salts thereof, selected from an amino acid, a hydroxycarboxylic acid, a hydroxylamine, a diamine, a lactam, a carboxylic alcohol, a carboxylic diol, a carboxylic polyol, a carboxylic diamine, or a carboxylic diacid.
The process of any one of the preceding claims, wherein the fermentation or bio-derived product comprises one or more compounds, or salts thereof, selected from 6-aminohexanoic acid, 7-aminoheptanoic acid, hexamethylenediamine, adipic acid, caprolactam, 1,6-hexanediol, or 1,5-pentamethylene diamine.
The process of any one of the preceding claims, wherein the fermentation or bio-derived product comprises biomass.
The process of any one of the preceding claims, wherein the aqueous stream is obtained from a milled ethanol production process.
A composition comprising a fermentation or bio-derived product produced by at least one process according to any one of the preceding claims, or as described in any of the Figures.
A composition comprising an aqueous stream, a gaseous stream, and an organism, wherein the organism or an equivalent or engineered equivalent thereof is a methanotroph or a hydrogen-metabolizing or CO-metabolizing chemolithotrophic organism, and wherein the organism is capable of mixotrophic metabolism of at least one gaseous substrate in the gaseous stream and at least one substrate in the aqueous stream.
A system for producing a fermentation or bio-derived product, comprising:
A biocatalytic process for producing a product, comprising:
The process of any one of the preceding claims, wherein the aqueous stream is from a bioethanol process.
Dependencies are inferred from the claim text.