Corynebacterium glutamicum for use in producing 2'-fucosyllactose
AssigneesSeoul National University R&Db Foundation, AP Technologies Corp.
InventorsJin-Ho SEO, Young-Wook CHIN, Hae-Yong JO
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Abstract
Provided is a method of producing 2′-fucosyllactose including culturing in a medium supplemented with lactose a recombinant Corynebacterium glutamicum transformed to express α-1,2-fucosyltransferase, transformed to express GDP-D-mannose-4,6-dehydratase, transformed to express GDP-L-fucose synthase, and transformed to express lactose permease, wherein the recombinant Corynebacterium glutamicum has phosphomannomutase and GTP-mannose-1-phosphate guanylyltransferase.
Claims3
A method of producing 2′-fucosyllactose comprising culturing in a medium supplemented with lactose a recombinant Corynebacterium glutamicum transformed to express α-1,2-fucosyltransferase, transformed to express GDP-D-mannose-4,6-dehydratase, transformed to express GDP-L-fucose synthase, and transformed to express lactose permease,
- wherein the recombinant Corynebacterium glutamicum has phosphomannomutase and GTP-mannose-1-phosphate guanylyltransferase.
Dependencies are inferred from the claim text.