Combination therapy with glucagon receptor antagonists
AssigneeNGM Biopharmaceuticals, Inc.
InventorZhonghao Liu
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Abstract
The present disclosure provides methods comprising a glucagon receptor antagonist in combination with an immunotherapeutic agent for treatment of disease.
Claims25
1-55. (canceled)
A method of treating diabetes in a human subject, the method comprising administering to the human subject a therapeutically effective amount of a glucagon receptor (GCGR) antagonist and a therapeutically effective amount of an immunotherapeutic agent.
A method of treating metabolic syndrome in a human subject, comprising administering to the human subject a therapeutically effective amount of a glucagon receptor (GCGR) antagonist and a therapeutically effective amount of an immunotherapeutic agent.
A method of improving beta cell function in a human subject, comprising administering to the human subject a therapeutically effective amount of a glucagon receptor (GCGR) antagonist and a therapeutically effective amount of an immunotherapeutic agent.
Dependencies are inferred from the claim text.