Peptide having anti-obesity and anti-diabetes efficacy and use thereof
AssigneeCaregen Co., Ltd.
InventorsYong Ji CHUNG, Eun Mi KIM
Life of this patent
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Abstract
The peptide of the present invention exhibits an anti-obesity effect by inhibiting fat accumulation and decomposing already accumulated fats as well as an outstanding anti-diabetes effect by effectively lowering blood sugar levels. The peptide of the present invention downregulates the expression of the adipogenic markers PPARγ, ACC and/or aP2, upregulates the expression of the lipolytic factors pHSL, AMPK-α1. CGI-58 and/or ATGL, and reduces sizes of adipocyte and levels of cholesterol in blood. The excellent activity and stability of the peptide of the present invention may be very advantageously applied to drugs and quasi-drug products.
Claims15
A peptide consisting of the amino acid sequence of SEQ ID NO:
- 2 or SEQ ID NO:
- 4.
A pharmaceutical composition for preventing or treating obesity, comprising one or more peptides selected from the group consisting of the peptide consisting of the amino acid sequence of SEQ ID NO:
- 2 or SEQ ID NO:
- 4 as an active ingredient.
A pharmaceutical composition for preventing or treating diabetes, comprising one or more peptides selected from the group consisting of the peptide consisting of the amino acid sequence of SEQ ID NO:
- 2 or SEQ ID NO:
- 4 as an active ingredient.
Dependencies are inferred from the claim text.