Anion exchange stationary phases based on crosslinked hydroxyalkylamine layer and glycidol

An anion exchange stationary phase comprises:

• A) a negatively charged substrate particle;
• B) a base condensation polymer layer attached to the negatively charged substrate particle, the base condensation polymer layer comprises a reaction product of
• i) a primary amine, and
• ii) a first polyepoxide compound;
• C) a first polyepoxide condensation reaction product covalently attached to the base condensation polymer layer, the first polyepoxide condensation reaction product comprises a reaction product of
• i) an amine group of the base condensation polymer layer, and
• ii) a second polyepoxide compound, in which the amine group of the base condensation polymer layer includes a positive charge so that the base condensation polymer layer is ionically coupled to the negatively charged substrate particle;
• D) a first ethanolamine condensation reaction product covalently attached to the first polyepoxide condensation reaction product, the first ethanolamine condensation reaction product comprises a reaction product of
• i) an epoxide group of the first polyepoxide condensation reaction product, and
• ii) a first ethanolamine;
• E) a second polyepoxide condensation reaction product covalently attached to the first ethanolamine condensation reaction product, the second polyepoxide condensation reaction product comprises a reaction product of
• i) an amine group of the first ethanolamine condensation reaction product, and
• ii) a third polyepoxide compound;
• F) a second ethanolamine condensation reaction product covalently attached to the second polyepoxide condensation reaction product, the second ethanolamine condensation reaction product comprises a reaction product of
• i) an epoxide group of the second polyepoxide condensation reaction product, and
• ii) a second ethanolamine;
• G) a third polyepoxide condensation reaction product covalently attached to the second ethanolamine condensation reaction product, the third polyepoxide condensation reaction product comprises a reaction product of
• i) an amine group of the second ethanolamine condensation reaction product, and
• ii) a fourth polyepoxide compound;
• H) a third ethanolamine condensation reaction product covalently attached to the third polyepoxide condensation reaction product, the third ethanolamine condensation reaction product comprises a reaction product of
• i) an epoxide group of the third polyepoxide condensation reaction product, and
• ii) a third ethanolamine;
• I) a fourth polyepoxide condensation reaction product covalently attached to the third ethanolamine condensation reaction product, the fourth polyepoxide condensation reaction product comprises a reaction product of
• i) an amine group of the third ethanolamine condensation reaction product, and
• ii) a fifth polyepoxide compound;
• J) a fourth ethanolamine condensation reaction product covalently attached to the fourth polyepoxide condensation reaction product, the fourth ethanolamine condensation reaction product comprises a reaction product of
• i) an epoxide group of the fourth polyepoxide condensation reaction product, and
• ii) a fourth ethanolamine;
• and
• K) a glycidol condensation reaction product covalently attached to the fourth ethanolamine condensation product, the glycidol condensation reaction product comprises a reaction product of
• i) an amine of the fourth ethanolamine condensation reaction product, and
• ii) a glycidol.