Method and system for concurrent photothermal ablation and interstitial photodynamic therapy
AssigneeHealth Research, Inc.
InventorsGal SHAFIRSTEIN, David Bellnier
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Abstract
The present disclosure provides a method and a system for treating a tissue using photodynamic therapy (PDT). A photosensitizer is administered to the tissue and one or more optical fibers are placed in the tissue. A treatment light is applied to the tissue by way of the one or more optical fibers. A temperature of the tissue is measured during application of the treatment light, and a fluence rate of the treatment light is modified based on the temperature of the tissue. For example, the fluence rate may be modified to be lower if the temperature of the tissue is higher than a predetermined threshold.)
Claims20
A method for treating a tissue, comprising:
- administering a photosensitizer to the tissue;
- providing one or more optical fibers placed in the tissue;
- applying a treatment light to the tissue by way of the one or more optical fibers, the treatment light having a fluence rate;
- measuring a temperature of the tissue during application of the treatment light;
- and
- modifying the fluence rate of the treatment light based on the temperature of the tissue.
A system for treating a tissue, comprising:
- a light source;
- an optical fiber operably coupled to the light source and configured to deliver a light dose of treatment light to the tissue;
- a temperature sensor;
- and
- a controller in communication with the temperature sensor and configured to modify a fluence rate of the treatment light based on a measured temperature.
Dependencies are inferred from the claim text.