Collagen and collagen like peptide based hyrdogels, corneal implants, filler glue and uses thereof
AssigneeNorth Grove Investments, Inc.
InventorsMay Griffith, Ayan Samanta, Jaganmohan Reddy Jangamreddy
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Abstract
The present invention provides for collagen and collagen like peptide based hydrogels, corneal implants, filler glue and uses thereof. The invention represents an advancement in the field of hydrogels, corneal implants, filler glue based on collagen and collagen like peptides. The invention discloses collagen and novel collagen like peptides crosslinked with DMTMM and their use in preparation of hydrogel, corneal implant and filler glue which are highly efficacious and robust as compared to existing corneal implants. Further, the invention relates to method of treating corneal defects and diseases.
Claims20
A modified nucleic acid comprising a nucleotide sequence selected from a group comprising of SEQ ID NO:7, SEQ ID NO:9, SEQ ID NO:11, SEQ ID NO:13 and SEQ ID NO:
- 15.
A collagen-like peptide (CLP) comprising the polypeptide of SEQ ID NO:5 operably fused to one or more peptide motifs selected from a group comprising of SEQ ID NO:
- 6, SEQ ID NO:
- 8, SEQ ID NO:
- 12 and SEQ ID NO:
- 14.
Dependencies are inferred from the claim text.