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US 2020/0046833 A1Published application
Agonist antibodies that bind human cd137 and uses thereof
AssigneeCompass Therapeutics LLC
InventorsPiotr BOBROWICZ, Paul WIDBOOM, Michael March SCHMIDT, Jason M. LAJOIE, Robert V. TIGHE, III, Cheuk Lun LEUNG, Ugur ESKIOCAK
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Abstract
The present disclosure relates to, inter alia, compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
Claims2
An isolated monoclonal antibody, or antigen binding portion thereof, that specifically binds human CD137, wherein the antibody or antigen binding portion binds human CD137 with an affinity (KD) of about 30-100 nM.
-103. (canceled)
Dependencies are inferred from the claim text.