Immunogenic composition, use and method of treatment
AssigneesGlaxoSmithKline Intellectual Property Development Limited, Glaxosmithkline Biologicals SA
InventorsCatherine COHET, Jeanne-Marie Josephine DEVASTER, David MAYHEW, Bruce MILLER, Ruth TAL-SINGER, Vincent WEYNANTS, Thomas WILKINSON
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Abstract
The present invention relates to immunogenic compositions comprising an immunogenic polypeptide from Haemophilus influenzae or an immunogenic fragment thereof and/or an immunogenic polypeptide from Moraxella catarrhalis or an immunogenic fragment thereof, for use in the treatment or prevention of a recurrence of an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) resulting from a bacterial infection in a subject.
Claims28
An immunogenic composition for the treatment or prevention of a recurrence of an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) associated with a bacterial infection in a subject comprising;
- an immunogenic polypeptide from Haemophilus influenzae or an immunogenic fragment thereof;
- and/or an immunogenic polypeptide from Moraxella catarrhalis or an immunogenic fragment thereof.
2-4. (canceled)
A method of treatment or prevention of a recurrence of an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) associated with a bacterial infection in a subject at risk of developing an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) recurrence, said method comprising administering to said subject a therapeutically effective amount of an immunogenic composition comprising:
- an immunogenic polypeptide from Haemophilus influenzae or an immunogenic fragment thereof;
- and/or an immunogenic polypeptide from Moraxella catarrhalis or an immunogenic fragment thereof.
9-10. (canceled)
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20-30. (canceled)
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41-61. (canceled)
Dependencies are inferred from the claim text.