Yeast-based immunotherapy for chordoma
AssigneesGlobeImmune, Inc., The USA, as represented by the Secretary, Dept. of Health and Human Services
InventorsTimothy C. RODELL, David APELIAN, Claudia PALENA, Jeffrey SCHLOM
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Abstract
Disclosed are methods of the treatment or prevention of chordoma which include the step of administering a yeast-based immunotherapeutic composition. The yeast-based immunotherapeutic composition preferably comprises a Brachyury antigen.
Claims36
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A method to prevent chordoma, delay the onset of chordoma, or improve the outcome of chordoma in an individual who has a history of familial chordoma, comprising administering to the individual an immunotherapeutic composition comprising:
- a) a yeast vehicle;
- and
- b) a cancer antigen comprising at least one Brachyury antigen;
- wherein, at the time of administering, the individual has not been diagnosed with chordoma.
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Dependencies are inferred from the claim text.