US 2020/0046800 A1 · BIOCIDAL AGENT

Abstract

The invention relates to medicine, specifically to new medicinal compositions that exhibit a biocidal, particularly antimicrobial and antiviral, effect. An agent is proposed that contains an alloferon analogue—the peptide H2N-His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly-COOH and the peptide HN2-(CH2)10-CO-Ile-Leu-Pro-D-Phe-Lys-D-Phe-Pro-D-Phe-D-Phe-Pro-D-Phe-Arg-Arg-NH2 in a mass ratio from 1:2 to 2:1 and excipients. The agent exhibits a combined antibacterial and antiviral effect and is promising for the treatment of vaginal herpes infection, including when complicated by bacterial infection.

Claims3

Dependent claims

An agent for local application exhibiting a biocidal effect, comprising a peptide H2N-His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly-COOH and excipients, wherein said agent additionally comprises a peptide HN2-(CH2)10-CO-Ile-Leu-Pro-D-Phe-Lys-D-Phe-Pro-D-Phe-D-Phe-Pro-D-Phe-Arg-Arg-NH2, wherein the ratio between said peptides is from 1:2 to 2:1 (wt. %)

Dependencies are inferred from the claim text.

Facts

Application

16/491,034Filed 29 Jan 2018

Priority

RU 20171160795 May 2017

Published

13 Feb 2020

Term ends

Not estimatedThe source records don’t support an estimate.

Classification10 codes

A61K 38/10
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof: peptides having 12 to 20 amino acids
A61K 9/0014
Galenical forms characterised by the site of application: skin, i.e. galenical aspects of topical compositions
A61K 9/06
Medicinal preparations characterised by special physical form: ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
A61K 38/08
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof: peptides having 5 to 11 amino acids

Biocidal agent

Life of this patent

Biocidal agent

Life of this patent

Abstract

Claims3