Transient Commensal Microorganism for Improving Gut Health
AssigneeEvolve Biosystems Inc
InventorsDavid KYLE, Samara FREEMAN-SHARKEY, Steven FRESE
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Abstract
The inventions described herein relate generally to administering compounds to promote mucosal healing in mammals in need thereof including, but not limited to humans. The compounds may include bifidobacteria and mammalian milk oligosaccharides.
Claims83
A medicament for treating a patient with intestinal distress comprising a mammalian milk oligosaccharide and a bifidobacteria that internalizes said mammalian milk oligosaccharide prior to its hydrolysis.
A method of treating gastrointestinal dysbiosis by providing a patient with a composition comprising a mammalian milk oligosaccharide from a mammalian milk source and bifidobacteria that internalizes said mammalian milk oligosaccharide prior to its hydrolysis for at least 5 days.
A composition comprising human milk oligosaccharides (HMO) and fucosylated glycans (SPF) and/or sialylated glycans (SPS), wherein the SPF and/or SPS are not of milk origin.
A composition comprising bovine milk oligosaccharides (BMO) and fucosylated glycans (SPF), wherein the SPF is not of milk origin.
A method of treating gastrointestinal dysbiosis comprising administering a mammalian milk oligosaccharide to a patient in need thereof, wherein the patient in need thereof is a patient with a dysbiotic microbiome.
Dependencies are inferred from the claim text.