Stem cells and methods of using them
OwnerJiunn-chern Yeh, Kathryn J. Petrucciinventors
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Abstract
This document relates to materials and methods involved in assessing and using stem cells. For example, materials and methods for determining if a stem cell (e.g., a mesenchymal stem cell) has an increased proliferation rate and/or an increased potential to differentiate into a bone cell are provided.
Claims16
A method for identifying a stem cell having increased potential to differentiate into a bone cell, wherein said method comprises:
- (a) determining that said stem cell has low expression of CD34 polypeptides;
- and
- (b) classifying said stem cell as having increased potential to differentiate into a bone cell.
A method for treating a mammal having a bone disease, said method comprising administering one or more stem cells having low expression of CD34 polypeptides to said mammal.
A method for treating a mammal having a broken bone, said method comprising administering one or more stem cells having low expression of CD34 polypeptides to said mammal.
Dependencies are inferred from the claim text.