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AssigneeMegmilk Snow Brand Co., Ltd.
InventorsYoshihiko TAKANO, Takayuki NARA, Ken KATO, Yoshikazu MORITA
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It is an object of the present invention to provide a chondrogenesis promoter that is safe and exhibits a chondrogenesis-promoting effect by daily ingestion. It is also an object of the invention to provide a proteoglycan synthesis promoter that exhibits a proteoglycan synthesis-promoting effect by ingestion. Provided are a chondrogenesis promoter and a proteoglycan synthesis promoter each containing a milk-derived basic protein fraction as an active ingredient. Synthesis of proteoglycan and formation of a cartilage can be promoted by oral ingestion of the milk-derived basic protein fraction. A hydrolysate of the milk-derived basic protein fraction also has a similar chondrogenesis-promoting effect.
A method of promoting chondrogenesis in a subject, comprising administering a milk-derived basic protein fraction or a decomposition product of a milk-derived basic protein fraction as an active ingredient to a subject in need thereof.
A method of promoting proteoglycan synthesis in a subject, comprising administering a milk-derived basic protein fraction as an active ingredient to a subject in need thereof.
A method of preventing, ameliorating, or treating joint disease in a subject, the method comprising ingestion of not less than 10 mg/day of a milk-derived basic protein fraction and/or a decomposition product of the milk-derived basic protein fraction as an active ingredient.
Dependencies are inferred from the claim text.