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US 2020/0046765 A1Published application
Topical antibiotic formulations
AssigneeAidance Skincare & Topical Solutions LLC
InventorsPerry ANTELMAN, Bharat MADHAVAN, Shalom LAMPERT
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Abstract
There are disclosed topical silver(II) antibiotic formulations. Other embodiments are also disclosed.
Claims21
A method of producing a silver(II) carboxylate or silver(II) carboxylate formulation, the method including the steps of:
- (a) mixing a carboxylic acid and silver(II) oxide to produce a reaction mixture;
- and (b) heating the reaction mixture to produce an aliphatic silver carboxylate, the silver of the aliphatic silver carboxylate having a nominal valence of 2.
An antimicrobial formulation comprising:
- (a) at least one silver-containing compound, including an anti-microbial agent containing an aliphatic silver carboxylate, said silver of said aliphatic carboxylate having a nominal valence of 2, said at least one silver-containing compound having an average valence of at least 1.1;
- and
- (b) a carrier base;
- said at least one silver-containing compound being dispersed within said base.
1 more element
19-21. (canceled)
A method of treating a topical infection in need of treatment, comprising applying to said infection a therapeutically effective amount of a formulation comprising:
- (a) at least one silver-containing compound, including an anti-microbial agent containing an aliphatic silver carboxylate, said silver of said aliphatic carboxylate having a nominal valence of 2, wherein an average valence of silver in said at least one silver-containing compound is within a range of 1.1 to 2;
- and
- (b) a carrier base;
- said at least one silver-containing compound being dispersed within said base, the formulation having a form of a cream, an emulsion, or an ointment, a total silver content of the formulation being within a range of 0.0005% to 7%, wherein a hydrocarbon structure of said aliphatic silver carboxylate is selected from the the group consisting of fully saturated, monounsaturated, and polyunsaturated structures.
1 more element
(canceled)
Dependencies are inferred from the claim text.