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US 2020/0046759 A1Published application
Therapeutic composition and methods
AssigneeViscera Labs, Inc.
InventorsSteven Taglienti, Steven L. Petruccelli, Oliseyenum MacDonald Nwose
Life of this patent
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Abstract
In exemplary embodiments, the disclosure provides a Colesevelam Colon Specific Drug Delivery System for use in treatment of, for example, cholestasis and/or cholestatic pruritus.
Claims52
An oral drug delivery system comprising:
- a) a core comprising a therapeutically effective amount of at least one active agent present in an amount of from about about 35% to about 65% w/w of the core, and a drug release controlling component capable of providing release of the active agent primarily in a region selected from the group consisting of the lower gastrointestinal tract, the large intestine, the jejunum, the ileum, the cecum, the colon, the rectum, and combinations thereof,
- b) an outer coating encasing the core, and optionally a plasticizer,
- wherein after ingestion by a patient the active agent is released primarily in the region selected from the group consisting of the lower gastrointestinal tract, the large intestine, the jejunum, the ileum, the cecum, the colon, the rectum, and combinations thereof.
Dependencies are inferred from the claim text.