Phospholipid Compositions
AssigneeMachavert Pharmaceuticals LLC
InventorsJakub STASZAK-JIRKOVSKY, Lukas KOBR, Gregory MIKNIS, Colleen HUDSON, Luca MONFREGOLA, Pavel JIRKOVSKY, Zboncáková MILADA, Jason DUEX, Pitchaimani KANDASAMY
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Abstract
Compositions involving a modified egg yolk extract for use as an effective anti-cancer agent are described. The modified egg yolk extract involves specific fractions of phosphatidylcholines and sphingomyelins modified and produced from a chemical synthesis applied to the extract that produce a beneficial effect on the inhibition of cancerous cell growth. Methods of administering these compositions are also described.
Claims1
A method of treating lung cancer in a human patient in need thereof comprising administering to said patient a pharmaceutical composition consisting of a plurality of phosphatidylcholine compounds and one or more pharmaceutically acceptable diluents, excipients, and/or carriers;
- wherein said plurality of phosphatidylcholine compounds comprise 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine and one or more phosphatidylcholines selected from the group consisting of:
- 1-palmitoleoyl-2-linoleoyl-sn-glycero-3-phosphocholine,
- 1-palmitoyl-2-α-linolenoyl-sn-glycero-3-phosphocholine,
- 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine,
- 1,2-dilinoleoyl-sn-glycero-3-phosphocholine,
- 1-palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine,
- 1-α-linolenoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine,
- 1-palmitoleoyl-2-oleoyl-sn-glycero-3-phosphocholine,
- 1-palmitoleoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine,
- 1-palmitoyl-2-osbondoyl-sn-glycero-3-phosphocholine,
- 1-oleoyl-2-arachidonoyl-sn-glycero-3-phosphocholine,
- 1-oleoyl-2-linoleoyl-sn-glycero-3-phosphocholine,
- 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine,
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,
- 1-oleoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine,
- 1,2-dioleoyl-sn-glycero-3-phosphocholine,
- 1-stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine, and
- 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine.
Dependencies are inferred from the claim text.