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US 2020/0046724 A1Published application
Beta-lactamase inhibitors and uses thereof
AssigneeArixa Pharmaceuticals, Inc.
InventorsERIC M. GORDON, JOHN FREUND, MARK A. GALLOP, MATTHEW ALEXANDER JAMES DUNCTON
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Abstract
β-Lactamase inhibiting compounds, therapeutic methods of using the f-lactamase inhibiting compounds, particularly in combination with β-lactam antibiotics and pharmaceutical compositions thereof are disclosed. The β-lactamase inhibiting compounds are suitable for oral administration.
Claims24
A compound of Formula (1):
- or a pharmaceutically acceptable salt thereof, wherein,
- each R1 is independently selected from C1-6 alkyl;
- and
- R3 is C1-6 alkyl.
1 more element
A compound, ethyl 3-(((((2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl)oxy)sulfonyl)oxy)-2,2-dimethylpropanoate) or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.