Compositions and methods for inhibiting kinases

A method of treating or preventing Parkinson's Disease, comprising administering to a subject an effective amount of an ATK inhibitor, wherein the ATK inhibitor is a compound having a structure of Formula (I) or a pharmaceutically acceptable salt thereof:

• wherein, independently for each occurrence,
• R1 is selected from hydrogen or lower alkyl, which may optionally be deuterated;
• and
• Cy1 is selected from substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, and substituted or unsubstituted heterocyclyl.