Methods and compositions for treating pain
AssigneeApkarian Technologies LLC
InventorA. Vania APKARIAN
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Abstract
The invention features combinations of dopaminergic agents and analgesic agents useful for treating pain. In particular, the combinations feature a low ratio of dopaminergic agent to analgesic agent. The dopaminergic agent can be an agonist of the dopamine receptor D1-like family or the dopamine receptor D2-like family. Such combinations potentiate analgesia to 1) alleviate acute pain, 2) prevent the transition from acute pain to chronic pain, and 3) manage chronic pain.
Claims26
1-82. (canceled)
A method of reducing pain in a subject in need thereof, said method comprising administering to the subject a dopaminergic agent and an analgesic agent, wherein the dopaminergic agent and analgesic agent are administered to the subject in a ratio of about 1:20 to about 1:2.
Dependencies are inferred from the claim text.