Aminocarbonylcarbamate compounds

A method for treating dopamine reuptake-related diseases or promoting smoking cessation comprising:

• administering to a mammal in need thereof a therapeutically effective amount of a compound of Formula (I) or pharmaceutically acceptable salt thereof,
• wherein
• X is independently halo, alkyl, alkoxy or nitro;
• m is 0, 1, 2, 3 or 4
• n is 1 or 2;
• R1 and R2 are independently H— or alkyl;
• R3 is H—, alkyl or aralkyl;
• and
• R4 is H— or aryl,
• wherein at least one of R1, R2, R3 and R4 is not H—,
• or a compound selected from the group consisting of:
• 2-amino-3-(2-chlorophenyl)propyl (aminocarbonyl)carbamate;
• 2-amino-3-(2,4-dichlorophenyl)propyl (aminocarbonyl)carbamate;
• 2-amino-3-(3,4-dichlorophenyl)propyl (aminocarbonyl)carbamate;
• 2-amino-3-(4-chlorophenyl)propyl (aminocarbonyl)carbamate;
• 2-amino-3-(3-chlorophenyl)propyl (aminocarbonyl)carbamate;
• 2-amino-3-(4-nitrophenyl)propyl (aminocarbonyl)carbamate;
• 2-amino-3-(4-tert-butylphenyl)propyl (aminocarbonyl)carbamate;
• 2-amino-3-(2-fluorophenyl)propyl (aminocarbonyl)carbamate;
• (2R)-2-amino-3-(2-chlorophenyl)propyl (aminocarbonyl)carbamate;
• (2R)-2-amino-3-(2,4-dichlorophenyl)propyl (aminocarbonyl)carbamate;
• (2R)-2-amino-3-(3,4-dichlorophenyl)propyl (aminocarbonyl)carbamate;
• 2-amino-3-phenylpropyl(aminocarbonyl)carbamate;
• (2R)-2-amino-3-phenylpropyl(aminocarbonyl)carbamate;
• and
• a pharmaceutically acceptable salt thereof;
• and
• wherein the dopamine reuptake-related disease is selected from the group consisting of fatigue, obesity, narcolepsy, fibromyalgia, cataplexy, drug addiction, sexual dysfunction, restless legs syndrome, bipolar disorder, depression, excessive daytime sleepiness, obsessive-compulsive disorder, and binge eating disorder.