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US 2020/0046254 A1Published application
Selection, segmentation and analysis of exhaled breath for airway disorders assessment
AssigneeCapnia, Inc.
InventorsAnthony D. WONDKA, Anish BHATNAGAR
Life of this patent
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Abstract
Methods and systems are described to automatically obtain and analyze a lung airway gas sample from the breath of a person for compositional analysis. These techniques may provide an improved method for example for accurately and reliably measuring nitric oxide for asthma assessment in young children and non-cognizant patients.
Claims25
An apparatus for analyzing nitric oxide levels in breath, comprising:
- a breathing sensor to measure a breathing pattern parameter;
- a breath sampling system comprising a plurality of valves to isolate sections of the breath gas sampling system;
- a first processor containing executable instructions for analyzing breathing pattern parameters of a plurality of breaths;
- a second processor containing executable instructions for establishing, based on the analyzed breathing pattern parameters of the plurality of breaths, a breathing pattern parameter criteria that delineates between a physiologically representative breath and a physiologically non-representative breath;
- a third processor containing executable instructions for determining whether a breathing pattern parameter of a breath, exhaled after the plurality of breaths, meets the breathing pattern parameter criteria;
- a fourth processor containing executable instructions for, in response to a determination that a breathing pattern parameter of the breath meets the breathing pattern parameter criteria, delineating at least a first section of the breath, a second section of the breath, and a third section of the breath, wherein the first section of breath is exhaled before the second section of breath and the second section of breath is exhaled before the third section of breath;
- a fifth processor containing executable instructions for controlling the plurality of valves to isolate the first section of breath, second section of breath, and third section of breath from each other;
- and
- an analyzer to analyze nitric oxide levels in at least one of the second section of the breath and the third section of the breath separately from the other.
6 more elements
A method of analyzing nitric oxide levels in breath, comprising:
- analyzing breathing pattern parameters of a plurality of breaths;
- establishing, based on the analyzed breathing pattern parameters of the plurality of breaths, a breathing pattern parameter criteria that delineates between a physiologically representative breath and a physiologically non-representative breath;
- determining whether a breathing pattern parameter of a breath, exhaled after the plurality of breaths, meets the breathing pattern parameter criteria;
- in response to a determination that a breathing pattern parameter of the breath meets the breathing pattern parameter criteria, delineating at least a first section of the breath, a second section of the breath, and a third section of the breath, wherein the first section of breath is exhaled before the second section of breath and the second section of breath is exhaled before the third section of breath;
- controlling a plurality of valves to isolate the first section of breath, second section of breath, and third section of breath from each other;
- and
- analyzing nitric oxide levels in at least one of the second section of the breath and the third section of the breath separately from the other.
4 more elements
Dependencies are inferred from the claim text.