Systems and Methods for Surgical Guide For Real-Time MRI Surgery

A guide system for guiding an elongated medical instrument toward a region of interest along a predetermined trajectory path, the guide system comprising:

• a base configured to be attached to a subject to receive the elongated medical instrument during an interventional medical procedure;
• an adjustment ring engaging the base;
• a plurality of ring adjustment controls configured to selectively fix the adjustment ring in a desired rotational orientation with respect to the base;
• a plurality of guide blocks, each guide block including a central axis and a guide hole configured to guide the elongated medical instrument along an angle of trajectory with respect to the central axis of the corresponding guide block and into the subject to perform the interventional medical procedure, wherein the guide holes of the plurality of guide blocks provide at least one of a different angle of trajectory or a different location within a given guide block;
• a plurality of block adjustment controls configured to selectively fix the given guide block in a desired rotational orientation with respect to the adjustment ring to present at least one of a unique angle of trajectory or location of the guide hole through which to receive the elongated medical instrument during the interventional medical procedure.

A method for guiding an elongated medical instrument toward a region of interest in a subject using a guide system and a magnetic resonance imaging (MRI) system, the guide system including a base, an adjustment ring, and a plurality of guide blocks, each of the guide blocks including a central axis and a guide hole configured to guide the elongated medical instrument along an angle of trajectory with respect to the central axis of the corresponding guide block, the method comprising:

• attaching the guide system to the subject proximate the region of interest;
• obtaining a first set of MRI images using the MRI system to orient the guide system with respect to the region of interest;
• determining, based on the first set MRI images, a trajectory path for the elongated medical instrument;
• selecting a guide block of the plurality of guide blocks based on the determined trajectory path;
• setting a rotational orientation of the adjustment ring with respect to the base based on the determined trajectory path;
• setting a rotational orientation of the selected guide block with respect to the adjustment ring based on the determined trajectory path;
• and
• guiding the elongated medical instrument through the guide hole of the selected guide block toward the region of interest.

A guide system for guiding an interventional medical instrument toward a region of interest (ROI) along a predetermined trajectory path, the guide system comprising:

• a base configured to be attached to a subject proximate to the ROI;
• an adjustment ring configured to be selectively fixed in one of a plurality of incremental rotational orientations with respect to the base;
• a plurality of detachable trajectory stems, each having a guide hole;
• and
• a plurality of guide blocks, each guide block configured to be selectively fixed in one of a plurality of incremental rotational orientations with respect to the adjustment ring and including a central axis and a trajectory stem aperture, the trajectory stem aperture being configured to receive a given detachable trajectory stem of the plurality of detachable trajectory stems and orient the corresponding guide hole of the given detachable trajectory stem along an angle of trajectory with respect to the central axis of the corresponding guide block;
• wherein each of the plurality of guide blocks includes at least one of differing angles of trajectory or differing locations of the guide hole from others of the plurality of guide blocks to provide a selectable, predetermined location of the guide hole and angle of trajectory when a given guide block of the plurality of guide blocks is received in the base.