# US 2020/0038433 A1 · Aqueous composition derived from seawater and seaweed

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- Number: US 2020/0038433 A1
- Document ID: US20200038433A1
- Status: Published application
- Kind: A1
- Application number: 16/338,470
- Filed: 2017-09-26
- Published: 2020-02-06
- Earliest claimed: 2016-10-03
- Assignees: Ys Lab
- Applicants: Ys Lab
- Inventors: ROXANE FAGON; MELODY DUTOT-WOLF; CAROLINE TANTER; MARC HEMON
- Web page: https://patentgrep.com/patent/US20200038433A1

## CPC

- A61K 31/737: Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate (A61K31/727 takes precedence)
- A61K 9/0014: {Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00)}
- A61K 9/0034: {Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants}
- A61K 9/0043: {Nose}
- A61K 9/0048: {Eye, e.g. artificial tears}
- A61K 9/006: {Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays}
- A61K 9/08: Solutions {(composition of solutions A61K47/00)}
- A61K 33/00: Medicinal preparations containing inorganic active ingredients
- A61K 33/06: Aluminium, calcium or magnesium; Compounds thereof {, e.g. clay}
- A61K 33/20: Elemental chlorine; Inorganic compounds releasing chlorine
- A61K 35/08: Mineral waters; Sea water
- A61K 36/03: Phaeophycota or phaeophyta (brown algae), e.g. Fucus
- A61K 47/02: Inorganic compounds
- A61K 47/46: Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
- A61P 29/00: Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P 37/04: Immunostimulants
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

An aqueous composition for the stimulation of the immune system for the purpose of preventing at least one of the diseases provoked by the invasion of one or several pathogenic agents through the skin, the eye or a mucous membrane. The aqueous composition is obtained from seawater and includes a sulphated polysaccharide contained in a seaweed.

## Claims

### Claim at position 1

1-14. (canceled)

### Claim 15

An aqueous composition to stimulate an immune system by stimulating an innate immunity to prevent at least one disease provoked by an invasion of at least one pathogenic agent through at least one of a skin, an eye and a mucous membrane, the aqueous composition obtained from 20 to 60% filtered seawater and comprising a sulphated polysaccharide contained in a seaweed.

### Claim 16 (depends on 15)

The aqueous composition according to claim 15, wherein the sulphated polysaccharide is a fucan.

### Claim 17 (depends on 15)

The aqueous composition according to claim 15, further comprising at least one water selected from a purified water, a distilled water and a demineralised water in a content from 40 to 80%.

### Claim 18 (depends on 15)

The aqueous composition according to claim 15, wherein the sulphated polysaccharide is extracted from a brown seaweed.

### Claim 19 (depends on 18)

The aqueous composition according to claim 18, wherein the brown seaweed is Ascophyllum nodosum.

### Claim 20 (depends on 15)

The aqueous composition according to claim 15, wherein the sulphated polysaccharide is in a content from 0.01 to 0.5%.

### Claim 21 (depends on 15)

The aqueous composition according to claim 15, wherein the sulphated polysaccharide has a mass from 2 to 21 kDa.

### Claim 22 (depends on 15)

The aqueous composition according to claim 15, wherein concentrations of elements of the aqueous composition are:
Cl (g/L)
5-15;
Na (g/L)
2.5-7;
Mg (g/L)
0.45-0.70;
Ca (g/L)
0.10-0.30; and
K (g/L)
0.10-0.30.

### Claim 23 (depends on 15)

The aqueous composition according to claim 15, wherein concentrations of elements of substances in the aqueous composition are:
Cl (g/L)
7.9-10.1;
Na (g/L)
4.3-5.3;
Mg (g/L)
0.51-0.63;
Ca (g/L)
0.16-0.22;
K (g/L)
0.15-0.23; and
Total sugars (g/L)
0.25-0.55.

### Claim 24 (depends on 15)

The aqueous composition according to claim 15, wherein a pH is from 6.5 to 8.5.

### Claim 25 (depends on 15)

The aqueous composition according to claim 15, wherein an osmolarity at 25° C. is from 400 to 550 mOsmol/Kg.

### Claim 26 (depends on 15)

The aqueous composition according to claim 15, wherein said mucous membrane is a nasal mucous membrane, an oral mucous membrane or a vaginal mucous membrane.

### Claim 27 (depends on 15)

The aqueous composition according to claim 15, to prevent inflammatory states of the mucous membrane.