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US 2020/0031784 A1Published application
Ozanimod addition salt crystal, preparation method, pharmaceutical composition, and uses
AssigneeSolipharma LLC
InventorsXiaohong SHENG, Xiaoxia SHENG, Jianfeng ZHENG
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Abstract
Disclosed is an ozanimod addition salt crystal, which is provided with one or more improved characteristics compared with a known ozanimod solid form. Also disclosed are a preparation method for the ozanimod addition salt crystal, a pharmaceutical composition of same, and uses thereof in preparing a medicament for diseases or disorders medically requiring optional regulation, activation, excitement, inhibition or antagonism of sphingosine-1-phosphate receptor.
Claims56
A crystalline form of an ozanimod addition salt with ozanimod having structure shown in formula (A) below,
- wherein the crystalline form of the ozanimod addition salt is a crystalline ozanimod mono-acid salt or a crystalline ozanimod hemi-acid salt.
Dependencies are inferred from the claim text.