Optical thermal method and system for diagnosing pathologies
AssigneesUniversité D'Aix-Marseille (Amu), Institut National de la Sante et de la Recherche Medicale
InventorsPhilipp Tsvetkov, François Devred
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Abstract
The invention concerns a method and a system for diagnosing a pathology in a mammal in need thereof. The method according to the invention comprises the following steps: collecting a blood, blood plasma or blood serum sample from said mammal, said biological sample comprising a protein mixture; obtaining an optical thermal denaturation profile of said biological sample; comparing said optical thermal denaturation profile of said biological sample with an optical thermal denaturation reference profile; and diagnosing the pathology.
Claims20
A method for diagnosing a pathology in a mammal in need thereof, comprising:
- collecting a biological sample from the mammal, the biological sample comprising a protein mixture, the biological sample being selected from the group consisting of blood, blood plasma and blood serum;
- obtaining an optical thermal denaturation profile of the biological sample;
- comparing the optical thermal denaturation profile of the biological sample with an optical thermal denaturation reference profile;
- and
- diagnosing the pathology.
A system for diagnosing a pathology in a mammal in need thereof, the system comprising:
- an apparatus for obtaining an optical thermal denaturation profile of a biological sample, the biological sample being selected from a group consisting of blood, blood plasma and blood serum;
- a database comprising reference thermal denaturation profiles obtained from biological samples of healthy mammals and/or of mammals for which the pathology was diagnosed;
- and
- a computing system for comparing the optical thermal denaturation profile of the biological sample with the reference thermal denaturation profile, and diagnosing the pathology.
Dependencies are inferred from the claim text.