Sample collection and handling for delayed analysis
AssigneeEssenlix Corporation
InventorsStephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi
Life of this patent
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Abstract
The present invention provides, among other things, devices, methods and applications of collecting, preserving, transporting, and analyzing tiny body fluids which have targeted biomarkers.
Claims157
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A device for sample collection, comprising:
- a plate having a sample contact surface, and
- spacers fixed on the sample contact surface and having a predetermined substantially uniform height and a predetermined constant inter-spacer-distance,
- wherein:
- the sample contact surface and the spacer fixed thereon comprise a sample attachment surface capable of a capillary action for sample liquid;
- and
- the spacers have a filling factor of at least 1%, the filling factor being the ratio of the spacer area in the sample contact surface to the total area of the sample contact surface.
A method of sample collection, comprising the steps of:
- (a) obtaining a plate, wherein:
- i. the plate has a sample contact surface;
- ii. spacers are fixed on the sample contact surface and have a predetermined substantially uniform height and a predetermined constant inter-spacer-distance;
- iii. the spacers have a filling factor of at least 1%, the filling factor being the ratio of the spacer area in the sample contact surface to the total area of the sample contact surface, and
- (b) contacting a thin layer of liquid sample with the sample contact surface of the plate,
- wherein:
- the sample contact surface and the spacer fixed thereon comprise a sample attachment surface capable of a capillary action for sample liquid, and
- the sample attachment surface allows at least part of the liquid sample to be deposited on the plate.
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Dependencies are inferred from the claim text.