# US 2020/0008299 A1 · Flexible printed electronics > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2020/0008299 A1 - Document ID: US20200008299A1 - Status: Published application - Kind: A1 - Application number: 16/267,253 - Filed: 2019-02-04 - Published: 2020-01-02 - Earliest claimed: 2016-10-21 - Assignees: Bao Tran - Inventors: Bao Tran; Ha Tran - Web page: https://patentgrep.com/patent/US20200008299A1 ## CPC - G16H 40/67: for remote operation - H05K 1/0393: {Flexible materials (H05K1/038 takes precedence; specific organic compositions are classified in H05K1/0313 and subgroups)} - A61B 5/0022: {Monitoring a patient using a global network, e.g. telephone networks, internet} - A61B 5/686: {Permanently implanted devices, e.g. pacemakers, other stimulators, biochips (A61B5/6861 takes precedence)} - H05K 1/0286: {Programmable, customizable or modifiable circuits (by programmable non-printed jumper connections H05K3/222)} - H05K 1/0313: {Organic insulating material} - H05K 1/0386: {Paper sheets (used as reinforcing materials for organic insulating substrates H05K1/0366)} - H05K 1/189: characterised by the use of flexible or folded printed circuits - H05K 3/10: in which conductive material is applied to the insulating support in such a manner as to form the desired conductive pattern - A61B 5/14517: {for sweat} - A61B 5/14532: {for measuring glucose, e.g. by tissue impedance measurement} - A61B 5/14546: {for measuring analytes not otherwise provided for, e.g. ions, cytochromes} - A61B 5/296: for electromyography [EMG] - A61B 5/6803: {Head-worn items, e.g. helmets, masks, headphones or goggles} - A61B 5/6805: {Vests, e.g. shirts or gowns} - A61B 5/685: {Microneedles} - A61B 5/7264: {Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems} - H05K 1/16: incorporating printed electric components, e.g. printed resistors, capacitors or inductors - H05K 2203/178: Demolishing, e.g. recycling, reverse engineering, destroying for security purposes; Using biodegradable materials - Y02A 90/10: Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation - Y02P 70/50: Manufacturing or production processes characterised by the final manufactured product - G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA - H05K: PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - Y02A: TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE - Y02P: CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS ## Abstract A biodegradable system includes a biodegradable substrate which can be a biodegradable paper or polymer. A biodegradable power source is printed or deposited above the substrate, and biodegradable processor and communication circuits are in turn formed on the substrate. The processor and wireless communication system can communicate with a remote computer to provide information about the source of the items (optionally tracked using the blockchain supply chain tracking), the relevant dates (production and expiration dates), any attempt to tamper with the packaging, and suitable warnings or usage instructions, for example. Optionally, a biodegradable display can render information to a customer, for example. ## Claims ### Claim 1 A method to fabricate biodegradable electronics, comprising: forming a biodegradable substrate; forming a biodegradable power; and forming a biodegradable processor, memory, and a wireless or optical communication circuit on the substrate. ### Claim 2 (depends on 1) The system of claim 1, wherein the biodegradeable substrate comprises a biodegradable paper or biodegradable polymer. ### Claim 3 (depends on 1) The method of claim 1, comprising printing or depositing components above the substrate. ### Claim 4 (depends on 1) The method of claim 1, wherein the processor and wireless communication system can communicate with a remote computer to provide information about the source of the items ### Claim 5 (depends on 1) The method of claim 1, comprising storing supply chain information on the substrate. ### Claim 6 (depends on 1) The method of claim 1, comprising storing production or expiration information on the substrate. ### Claim 7 (depends on 1) The method of claim 1, comprising storing tamper-proof information on the substrate. ### Claim 8 (depends on 1) The method of claim 1, comprising storing blockchain information on the substrate. ### Claim 9 (depends on 1) The method of claim 1, comprising forming a biodegradable display on the substrate. ### Claim 10 (depends on 1) The method of claim 1, comprising forming a bacteria storage on the substrate. ### Claim 11 (depends on 10) The method of claim 10, comprising forming a biodegradable food storage coupled to the bacteria storage on the substrate. ### Claim 12 (depends on 10) The method of claim 10, comprising forming a liquid storage coupled to the bacteria storage on the substrate, wherein liquid is selectively introduced to the bacteria to activate the bacteria to provide energy. ### Claim 13 (depends on 1) The method of claim 1, comprising detecting a predetermined substance. ### Claim 14 (depends on 13) The method of claim 13, comprising: functionalizing a macromolecule with a material to couple to a predetermined substance; forming the functionalized macromolecule on the substrate; exposing the macromolecule to an operating environment to attach the macromolecule to the predetermined substance; measuring an electrical characteristic indicative of the presence of the predetermined substance; and indicating a presence of the substance if the electrical characteristic is greater than or less than a predetermined range. ### Claim 15 (depends on 14) The method of claim 14, comprising securing the macromolecule to a skin to capture sweat. ### Claim 16 (depends on 13) The method of claim 13, comprising detecting one or more of metabolite, glucose, lactate, electrolyte, sodium, potassium. ### Claim 17 (depends on 13) The method of claim 13, wherein the substance comprises a bio-marker, comprising exposing the macromolecule to blood. ### Claim 18 (depends on 13) The method of claim 13, comprising securing a macromolecule to a skin with microneedles to expose the macromolecule to subdermal blood. ### Claim 19 (depends on 18) The method of claim 18, comprising forming an implantable medical device with an exposed region to expose the macromolecule to blood and implanting the device inside a person. ### Claim 20 (depends on 17) The method of claim 17, wherein the bio-marker comprises one or more cancer biomarkers, further comprising detecting cancer from DNA fragments circulating in the blood and wherein the material comprises a predetermined DNA sequence, further comprising: functionalizing the macromolecule with a second material to bond with a second DNA sequence complementary to the predetermined DNA sequence; during operation, generating a complementary DNA sequence from cell material in the blood and coupling the complementary DNA sequence to the second material; characterizing a second electrical characteristic indicative of the presence of the second DNA sequence, applying differential analysis to the first and second electrical characteristics to accurately determine a presence of the predetermined DNA sequence; and detecting the presence of the bio-marker using machine learning.