Automatic Generation of User and Non-User Cohorts for The Estimation of Drug's Effect from Longitudinal Observational Data

A system for conducting an observational trial of a drug under study, the system comprising a processor, memory accessible by the processor, and computer program instructions stored in the memory and executable by the processor to perform:

• receiving data relating to a plurality of patients, the data including drug prescription information for each patient;
• assigning each of the plurality of patients to a trial cohort based on the drug prescription information;
• setting an index date for each of the plurality of patients;
• and
• conducting an observational drug trial using the generated cohorts and index dates.

A computer program product for conducting an observational trial of a drug under study, the computer program product comprising a non-transitory computer readable storage having program instructions embodied therewith, the program instructions executable by a computer, to cause the computer to perform a method comprising:

• receiving data relating to a plurality of patients, the data including drug prescription information for each patient;
• assigning each of the plurality of patients to a trial cohort based on the drug prescription information;
• setting an index date for each of the plurality of patients;
• and
• conducting an observational drug trial using the generated cohorts and index dates.