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US 2020/0003789 A1Published application
Neural proteins as biomarkers for nervous system injury and other neural disorders
AssigneesUniversity of Florida Research Foundation, Inc., Banyan Biomarkers, Inc.
InventorsKevin Ka-Wang WANG, Monika OLI, Ming-Cheng LIU
Life of this patent
Estimating the term…
Abstract
The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury.
Claims21
(canceled)
A method for detecting Ubiquitin C-terminal Hydrolase L1 (UCH-L1), comprising:
- detecting whether UCH-L1 is present in a biological sample collected from a subject suspected of having a traumatic brain injury (TBI) by contacting the biological sample with an anti-UCH-L1 antibody and detecting binding of the antibody to UCH-L1.
A method for detecting Ubiquitin C-terminal Hydrolase L1 (UCH-L1), comprising:
- detecting whether UCH-L1 is present in a biological sample collected from a subject suspected of having a traumatic brain injury (TBI) by contacting the biological sample with an anti-UCH-L1 antibody and detecting binding of the antibody to UCH-L1, wherein the TBI is caused by a traumatic insult.
Dependencies are inferred from the claim text.