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US 2020/0002684 A1Published application
Methods and compositions for producing vitamin k dependent proteins
AssigneeThe University of North Carolina at Chapel Hill
InventorsDarrel W. Stafford, Tao Li
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Abstract
The present invention relates to methods and compositions for improving the productivity of recombinant vitamin K dependent protein expression in host cells.
Claims1
A host cell comprising a recombinant nucleic acid coding for a vitamin K epoxide reductase (VKOR) or a functionally active derivative thereof, and a recombinant nucleic acid coding for a vitamin K dependent protein or a functionally active derivative thereof, wherein both the recombinant VKOR and the recombinant Vitamin K dependent protein are expressed in said host cell.
Dependencies are inferred from the claim text.