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US 2020/0002318 A1Published application
Azetidinyloxyphenylpyrrolidine compounds
AssigneeEli Lilly and Company
InventorsGary G. Deng, Danwen Huang, Cynthia Darshini Jesudason, Joshua O. Odingo
Life of this patent
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Abstract
The invention provides certain azetidinyloxyphenylpyrrolidine compounds, particularly compounds of formula I, and pharmaceutical compositions thereof. The invention further provides methods of using a compound of formula I to treat overactive bladder.
Claims13
A compound of the formula
- wherein
- R is
- R1 is CH3, CN, Cl or CF3;
- or a pharmaceutically acceptable salt thereof;
- provided when R1 is CH3 it is not attached at the 5 position.
2 more elements
The compound which is (2S)-3-[(3S,4S)-3-[(1R)-1-hydroxyethyl]-4-(4-methoxy-3-{[1-(5-chloropyridin-2-yl)azetidin-3-yl]oxy}phenyl)-3-methylpyrrolidin-1-yl]-3-oxopropane-1,2-diol.
A compound selected from the group consisting of:
- or a pharmaceutically acceptable salt thereof.
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Dependencies are inferred from the claim text.