Per-oral negative contrast agent for abdominal ct
AssigneeLument AB
InventorsLucia Casal-Dujat, Olof Böök, Ingvar Adnerhill, Rickard Öste, Thomas Fork
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Abstract
An edible negative contrast agent for CT imaging of the gastrointestinal tract intended for oral intake. The contrast agent is a fluid, aqueous foam displaying a CT density contrast value in the range −300 to −800 HU and having a consistency of 7 to 12 cm as measured with Bostwick consistometer. The contrast agent comprises an aqueous continuous liquid phase having a pH of 6.5 to 8.0 and gas bubbles dispersed in the continuous aqueous liquid phase. The aqueous continuous liquid phase comprises a surfactant, the surfactant being a protein, a hydrocolloid acting as foam stabilizer, a buffering agent, and water.
Claims25
An edible negative contrast agent for CT imaging of the gastrointestinal tract intended for oral intake, the contrast agent being a fluid, aqueous foam displaying a CT density contrast value in the range −300 to −800 HU, wherein the contrast agent comprises an aqueous continuous liquid phase having a pH of 6.5 to 8.0, the aqueous continuous liquid phase comprising:
- a surfactant, the surfactant being a protein;
- a hydrocolloid acting as foam stabilizer;
- a buffering agent;
- and
- water;
- and gas bubbles dispersed in the continuous aqueous liquid phase, the contrast agent having a consistency of 7 to 12 cm as measured with Bostwick consistometer over 30 seconds at 23±1° C.
Dependencies are inferred from the claim text.