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US 2019/0338035 A1Published application
Constructs targeting histone h3 peptide/mhc complexes and uses thereof
AssigneeEureka Therapeutics, Inc.
InventorsVivien Wai-Fan CHAN, Hong LIU, Yoko NAKANO, Yiyang XU
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Abstract
The present application provides constructs comprising an antibody moiety that specifically binds to a complex comprising a histone H3 peptide and an MHC class I protein. Also provided are methods of making and using these constructs.
Claims34
An isolated anti-HMC construct comprising an antibody moiety that specifically binds to a complex comprising a histone H3 peptide and a major histocompatibility (MHC) class I protein (“HMC”).
Dependencies are inferred from the claim text.