US 2019/0337977 A1Published application

Means and methods for site-specific functionalization of polypeptides

AssigneesLudwig-Maximilians-Universitat Munchen, Forschungsverbund Berlin E.V.

InventorsHeinrich LEONHARDT, Jonas HELMA, Dominik SCHUMACHER, Christian HACKENBERGER

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Abstract

The present invention provides means and methods for equipping a polypeptide of interest at its C-terminus with a versatile adaptor amino acid that allows the functionalization of the polypeptide of interest.

Claims14

Dependent claims

A polypeptide wherein said polypeptide is a polypeptide other than tubulin and has a length of more than 19 amino acids, wherein the polypeptide comprises a recognition sequence for tubulin-tyrosinate liages (TTL) at its C-terminus.

Dependencies are inferred from the claim text.

Facts

Application: 16/225,522Filed 19 Dec 2018
Priority: LU 9258829 Oct 2014
Published: 7 Nov 2019
Term ends: Not estimatedThe source records don’t support an estimate.

Classification8 codes

C07K 1/1075
By covalent attachment of residues or functional groups: by covalent attachment of amino acids or peptide residues
C07K 14/00
Peptides having more than 20 amino acids
C12P 21/005
Preparation of peptides or proteins: glycopeptides, glycoproteins
C12P 21/02
Preparation of peptides or proteins: having a known sequence of two or more amino acids, e.g. glutathione

Family

Application15/521,675Division · filed 25 Apr 2017
Application16/225,522Division
US 10,208,084 B2Related patent
US 10,745,437 B2Related patent
US 2017/0349625 A1Published application
US 2019/0337977 A1This patent

From the US filing history. Foreign family members aren’t listed.

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