Novel biaromatic propynyl compounds, pharmaceutical and cosmetic compositions containing same, and uses thereof

A bi-aromatic propynyl compound, wherein the compound corresponds to general formula (I) below:

• in which:
• Ar represents a radical selected from the group of radicals of formulas (a)-(e) below consisting of:
• R5 having the meaning given below,
• R1 represents:
• (i) a hydrogen atom
• (ii) a —CH3 radical
• (ii) a —CH2—O—R6 radical
• (iv) an —O—R6 radical
• (v) a —CO—R7 radical,
• (vi) an —S(O)tR9 radical
• R6, R7, R9 and t having the signification given below,
• R2 and R3 represent a hydrogen atom, a linear or branched alkyl radical having 1 to 20 carbon atoms, an —OR6 radical or an —SR6 radical, R6 having the meaning given below, given that R2 and R3, taken together, can form with the adjacent aromatic ring a 5- or 6-member ring optionally substituted by methyl groups and/or optionally interrupted by an oxygen or sulfur atom,
• R4 represents a hydrogen atom, a halogen atom, a lower alkyl radical or an —OR6 radical, R6 radical having the meaning given below,
• given that in all of the preceding:
• R6 represents a hydrogen atom, a lower alkyl radical, linear or branched alkyl radical having 1 to 20 carbon atoms, an —O—CH3—R9 radical or a —CO—R9 radical, R9 having the meaning given below,
• R7 represents:
• (a) a hydrogen atom
• (b) a lower alkyl radical
• (c) a radical of formula:
• R′ and R″ having the meaning given below,
• (d) an —OR8 radical, R8 having the meaning given below,
• R8 represents a hydrogen atom, a linear or branched alkyl radical having 1 to 20 carbon atoms, an alkenyl radical, a mono- or polyhydroxyalkyl radical, an optionally substituted aryl or aralkyl radical or a sugar residue or an amino acid or peptide residue,
• R9 represents a lower alkyl radical, or a linear or branched alkyl radical having 1 to 20 carbon atoms,
• R′ and R″ represent a hydrogen atom, a lower alkyl radical, a mono- or polyhydroxyalkyl radical, an optionally substituted aryl radical or an amino acid or peptide residue or sugar residue, or even, taken together, form a heterocycle,
• t is a whole number equal to 0, 1 or 2 and
• salts and optical and geometric isomers thereof.