Fluid manipulation cartridge and controller mechanism

The cartridge according to any preceding claim wherein the sample processing chamber comprises a closed sample processing well which is at least partially formed to be expandable.

The cartridge according to any preceding claim wherein the sample processing chamber comprises a meter well fluidly connected by a third channel to a closed meter overflow well.

The cartridge according to any preceding claim, wherein the second channel port is the only route through which liquid may enter or exit the sample processing chamber.

The cartridge according to any preceding claim wherein the sample analysis location further comprises a detection location connected by a fourth channel to the sample analysis well, optionally wherein the detection location comprises a lateral flow device.

The cartridge according to any preceding claim wherein the first channel comprises a primary first channel portion, a secondary first channel portion and a sample receiving well positioned therebetween, the sample receiving well optionally being connected to a sample overflow well by a fifth channel, the secondary first channel portion comprising a first channel valve.

The cartridge according to any preceding claim comprising a first cartridge body in which is formed one or more of the sample processing chamber, the sample analysis well and at least a portion of one or more of the first and second channels.

The cartridge according to any preceding claim comprising a first cartridge body in which is formed the sample analysis well and a second cartridge body in which is formed the sample entry location and a liquid-containing well connected by a sixth channel to the sample analysis well, the sixth channel being formed by a primary sixth channel portion formed in the second cartridge body and a secondary sixth channel portion formed in the first cartridge body, the first and second cartridge bodies being arranged to enable fluid connection between the primary and secondary sixth channel portions at a second junction.

The cartridge according to any preceding claim wherein the sample entry location comprises a sample receiving container in fluid connection with the first channel, the container having an interior and an entrance aperture.

A fluid dispensing system comprising a storage chamber in fluid connection with a dispensing chamber, the dispensing chamber being sealed with a film to form a closed chamber configuration and comprising an integral pin moveable from a first position to a second film-piercing position, placing the dispensing chamber in an open chamber configuration.