Surgical sealant
AssigneeNational Institute for Materials Science
InventorTetsushi TAGUCHI
Life of this patent
Estimating the term…
Abstract
A surgical sealant consisting of (1) a first agent comprising a gelatin derivative, wherein the gelatin derivative (a) has a weight average molecular weight of from 10,000 to 50,000; (b) has a hydrophobic group bonded thereto, the hydrophobic group being an alkyl group having 6 to 18 carbon atoms; (c) has a molar ratio of imino group/amino group of the gelatin derivative ranging from 1/99 to 30/70; and (d) comprises a structure represented by the following formula: GltnNH—CHR1R2, wherein “Gltn” represents a gelatin residue, R1 is the hydrophobic group, and R2 is a hydrogen atom or the hydrophobic group; and (2) a second agent comprising a crosslinking agent for the gelatin derivative.
Claims7
A surgical sealant consisting of
- (1) a first agent comprising a gelatin derivative, wherein the gelatin derivative
- (a) has a weight average molecular weight of from 10,000 to 50,000;
- (b) has a hydrophobic group bonded thereto, the hydrophobic group being an alkyl group having 6 to 18 carbon atoms;
- (c) has a molar ratio of imino group/amino group of the gelatin derivative ranging from 1/99 to 30/70;
- and
- (d) comprises a structure represented by the following formula:
- GltnNH—CHR1R2
- wherein “Gltn” represents a gelatin residue, R1 is the hydrophobic group, and R2 is a hydrogen atom or the hydrophobic group;
- and
- (2) a second agent comprising a crosslinking agent for the gelatin derivative, wherein said surgical sealant is resistant to radiation sterilization.
Dependencies are inferred from the claim text.