Wound dressing materials

A method of making a wound dressing, the method comprising the steps of:

• forming an aqueous dispersion, the aqueous dispersion comprising a bioabsorbable carrier material, N-acetyl cysteine or a salt thereof, a stabilized ascorbate, and an aqueous solvent, wherein a weight ratio of N-acetyl cysteine or a salt thereof to the stabilized ascorbate is from about 1:4 to about 4:1;
• and
• freeze-drying or solvent-drying the aqueous dispersion to produce an active layer;
• wherein
• the wound dressing comprises the active layer;
• the active layer comprises a wound-facing side, the bioabsorbable carrier material, the N-acetyl cysteine or a salt thereof, and the stabilized ascorbate, where a weight ratio of N-acetyl cysteine or a salt thereof to the stabilized ascorbate is from about 1:4 to about 4:1 in the active layer;
• and
• the stabilized ascorbate comprises a member selected from the group consisting of ascorbate 2-phosphate or polyphosphate compounds, trisodium L-ascorbyl-2-monophosphate, 2-phospho-L-ascorbic acid trisodium salt, magnesium ascorbyl phosphate (MAP), L-ascorbic acid mono(dihydrogen phosphate) magnesium salt, magnesium L-ascorbic acid-2-phosphate, trisodium L-ascorbyl-2-polyphosphate, and a combination of any two or more thereof.