Polyurethane-hydrogel composition comprising chlorhexidine

Abstract

The invention is directed to a composition comprising: a polyurethane substrate; a hydrogel forming polymer on at least one of the two faces of the polyurethane substrate; and chlorhexidine on the at least one face comprising the hydrogel forming polymer; wherein the hydrogel polymer is covalently linked to the polyurethane substrate. The invention is also directed to a dressing in comprising the composition and to a process for the preparation of the composition, the process comprising the following steps: a) in impregnating at least one face of a polyurethane substrate with a solution comprising a reactive diolefin and a free radical initiator; b) extracting the polyurethane from the solution and, after drying, immerging the polyurethane in a solution containing the initiator catalyst and the hydrogel forming polymer to obtain PU covalently bond to a hydrogel forming polymer; c) extracting the polyurethane-hydrogel composition and drying in air; d) immerging the product of step iii) into an aqueous solution of chlorhexidine; e) collecting the polyurethane-hydrogel-chlorhexidine product from the solution and drying the obtained composition in air.

Dependencies are inferred from the claim text.