Compositions to treat ultraviolet (uv)-induced skin injury
AssigneeMayo Foundation for Medical Education and Research
InventorsStephen C. Ekker, Debabrata Mukhopadhyay, Priyabrata Mukherjee, Victoria M. Bedell, Luke H. Hoeppner, Stella P. Hartono
Life of this patent
Estimating the term…
Abstract
This document relates to materials and methods for administering (e.g., topically administering) one or more vascular endothelial growth factor (VEGF) inhibitors to reduce and/or treat ultraviolet (UV)-induced skin injury. For example, compositions including one or more VEGF inhibitors that can be administered (e.g., topically administered) to a mammal to reduce and/or treat UV-induced skin injury following UV exposure are provided.
Claims25
A composition comprising a vascular endothelial growth factor (VEGF) inhibitor, wherein the composition is formulated for topical application to the skin of a mammal.
A method for treating a UV-induced skin injury in a mammal, said method comprising:
- topically administering a composition comprising vascular endothelial growth factor (VEGF) inhibitor to a mammal exposed to ultraviolet (UV) light;
- wherein a symptom of said UV-induced skin injury is reduced.
A method for treating a UV-induced skin cancer in a mammal, said method comprising:
- topically administering a composition comprising vascular endothelial growth factor (VEGF) inhibitor to a mammal identified as having said UV-induced skin cancer;
- wherein tumor growth of said UV-induced skin cancer is reduced.
Dependencies are inferred from the claim text.